The attack occurred on the outskirts of Ghazni, capital of the eastern province of Ghazni, which has seen regular fighting between the Taliban and government forces.
“We have received 26 bodies and 17 wounded so far. All of them are security personnel,” Baz Mohammad Hemat, director of Ghazni hospital, told AFP.
Nasir Ahmad Faqiri, a member of Ghazni provincial council, confirmed the death toll.
Interior ministry spokesman Tariq Arian confirmed that a suicide bomber had detonated a vehicle full of explosives in Ghazni, but did not offer any immediate figure for casualties.